We are a fully integrated biopharmaceutical company. Our team works to address complications of kidney disease. We have both a commercially available medicine and a late stage oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), vadadustat.  Vadadustat and other HIF-PHIs are based on Nobel Prize-winning science.

Vadadustat is an investigational drug that has not been approved by the U.S. Food and Drug Administration (FDA) or any regulatory authority for use outside of Japan. Within Japan, vadadustat is approved and marketed by Mitsubishi Tanabe Pharma Corporation under the trade name VAFSEO™ as a treatment for anemia due to CKD in both dialysis-dependent and non-dialysis dependent adult patients.